Carbidopa

Product Detail

Basic information ofCarbidopa:


Name	Carbidopa
Alias	1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)-decahydroquinoxaline
CAS Number	38821-49-7
Molecular Formula	C10H16N2O5
Molecular Weight	244.24
QualityStandard	USP32
Package Size	25kg/drum, according your requirement
Brief Introduction	Carbidopa with strong outer peripheral dopa decarboxylase inhibitors. Easy through the blood-brain barrier, in combination with levodopa, it suppresses only the outer peripheral dopa decarboxylase activity, reducing the production of dopamine in peripheral tissues, reduce adverse reactions outer periphery, thereby enabling an increase in levodopa into the hub, improve brain concentration of dopamine, enhance the efficacy of levodopa, it is an important adjunct to levodopa. Carbidopa alone invalid, clinical carbidopa and levodopa is usually 1:10 or 1: 4 Proportion compound preparation

Use of Carbidopa:

For various causes Parkinson's disease.

COA ofCarbidopa:

ITEMS	SPECIFICATION	RESULTS
Appearance	A white or creamy white powder	Creamy white powder
Identification IR HPLC	IR spectrum is consistent with carbidopa CRS Conform with the retention time of the major peak in the chromatogram	Conforms Conforms
Specific rotation	-21.0º ~-23.5º	-22.7º
Loss on drying	6.9%-7.9%	7.4%
Residue on ignition	=0.1%	0.05%
Heavy metals	=0.001%	<0.001%
Limit of methyldopa and carbidopa related components A Methyldopa Carbidopa related components A Any unknown impurity	=0.5% =0.5% =0.10%	0.26% <LOD(0.02%) 0.09%
Residual solvents Trichloromethane Ethanol	=0.006% =0.10%	<LOD (0.4PPM) 0.0001%
ASSAY	98.0%--102.0%	100.1%
Conclusion:The batch conforms to USP32 specifications.

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